⚠️New Publication Alert - Congratulations Stephen

Congratulations Stephen on your recently accepted article in BiorgMedChem entitled “Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue". This article was published as part of the special issue on bioisosterism in drug discovery.

The paper highlights recent advances in developing novel therapeutic agents to combat osteoarthritis by targeting Tissue inhibitor of metalloproteinases 3 (TIMP-3). Suramin analogues have previously been shown to inhibit cartilage degradation through its ability to block endocytosis and intracellular degradation TIMP-3.

Read it here: https://www.sciencedirect.com/science/article/pii/S0968089623002729